Journal article

Longitudinal associations of modifiable lifestyle factors with positive depression-screen over 2.5-years in an international cohort of people living with multiple sclerosis

KL Taylor, S Simpson, GA Jelinek, SL Neate, AM De Livera, CR Brown, E O’kearney, CH Marck, TJ Weiland

Frontiers in Psychiatry | FRONTIERS MEDIA SA | Published : 2019

Abstract

Background: Depression is common and has a significant impact on quality of life for many people with multiple sclerosis (MS). A preventive management approach via modification of lifestyle risk factors holds potential benefits. We examined the relationship between modifiable lifestyle factors and depression risk and the change in depression over 2.5 years. Methods: Sample recruited using online platforms. 2,224 (88.9%) at baseline and 1,309 (93.4%) at 2.5 years follow up completed the necessary survey data. Depression risk was measured by the Patient Health Questionnaire-2 (PHQ-2) at baseline and Patient Health Questionniare-9 (PHQ-9) at 2.5-years follow-up. Multivariable regression models ..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

The study was funded by the Bloom Foundation, Wal Pisciotta, and the Horne Family Charitable Trust. CM is funded by an Early Career Fellowship from the National Health and Medical Research Council (ID 1120014). Funding was received from The Royal Australian and New Zealand College of Psychiatrists, New Investigator Grant (KT).